The European Association for Cancer Research conference « Overactivation of Oncogenic Signalling as a Potential Cancer Treatment Strategy » will explore a seemingly paradoxical approach to cancer therapy, based on the deliberate hyper-activation of cancer-relevant signalling pathways. Accumulating evidence suggests that this leads to cell death caused by a further activation of cellular stress responses. This conference will focus on ways to hyperactivate oncogenic signalling and how the vulnerabilities associated with this hyper-activated state can be identified. The following topics will be covered:
